How to create a do-not-reply email address?

==== Required information ====
- iRedMail version: 1.8.1
- Store mail accounts in which backend (LDAP/MySQL/PGSQL): LDAP
- Linux/BSD distribution name and version: CentOS 6.3
- Related log if you're reporting an issue:
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How would I go about creating a "do-no-reply" email address so that informational emails could be sent out, but iRedMail would not accept or store replies to the email?

Is it as simple as unchecking "Receiving mails for this account on mail server" in Advanced under the account?  By unchecking this setting, are there any other effects that I should be aware of?

Thanks,

Jon